img Leseprobe Leseprobe

Computational Drug Design

A Guide for Computational and Medicinal Chemists

D. C. Young

Amazon iTunes Hugendubel Bü kobo Osiander Google Books Barnes&Noble Legimi
* Affiliatelinks/Werbelinks
Hinweis: Affiliatelinks/Werbelinks
Links auf sind sogenannte Affiliate-Links. Wenn du auf so einen Affiliate-Link klickst und über diesen Link einkaufst, bekommt von dem betreffenden Online-Shop oder Anbieter eine Provision. Für dich verändert sich der Preis nicht.

John Wiley & Sons img Link Publisher

Naturwissenschaften, Medizin, Informatik, Technik / Chemie


Helps you choose the right computational tools and techniques tomeet your drug design goals Computational Drug Design covers all of the majorcomputational drug design techniques in use today, focusing on theprocess that pharmaceutical chemists employ to design a new drugmolecule. The discussions of which computational tools to use andwhen and how to use them are all based on typical pharmaceuticalindustry drug design processes. Following an introduction, the book is divided into threeparts: * Part One, The Drug Design Process, sets forth a variety ofdesign processes suitable for a number of different drugdevelopment scenarios and drug targets. The author demonstrates howcomputational techniques are typically used during the designprocess, helping readers choose the best computational tools tomeet their goals. * Part Two, Computational Tools and Techniques, offers a series ofchapters, each one dedicated to a single computational technique.Readers discover the strengths and weaknesses of each technique.Moreover, the book tabulates comparative accuracy studies, givingreaders an unbiased comparison of all the available techniques. * Part Three, Related Topics, addresses new, emerging, andcomplementary technologies, including bioinformatics, simulationsat the cellular and organ level, synthesis route prediction,proteomics, and prodrug approaches. The book's accompanying CD-ROM, a special feature, offersgraphics of the molecular structures and dynamic reactionsdiscussed in the book as well as demos from computational drugdesign software companies. Computational Drug Design is ideal for both students andprofessionals in drug design, helping them choose and take fulladvantage of the best computational tools available. Note: CD-ROM/DVD and other supplementary materials arenot included as part of eBook file.


(ChemMedChem, 2010)
"In conclusion, this book provides a comprehensive introduction tocomputational drug design for scientists (e.g. medicinal chemistsand pharmacologists, particularly at industrial level) who are notfamiliar with computational methods and who wish to discusssimulation outcomes with colleagues from computational departments.It provides a similarly comprehensive introduction for students,while also covering aspects not usually touched on by othercomputational textbooks. Students will then need to deepen theirmathematical and theoretical background to become robustcomputational drug designers."
(Journal of Medicinal Chemistry, August2009)
"The book has been written in very lucid and readablelanguage."
(JACS Book Reviews,June 2009)
"As the author states, 'this book is veryindustry-centric' and was designed to explore the drug designprocess through the computational techniques that are used in atypical pharmaceutical industry."
Weitere Titel in dieser Kategorie
Cover Quantum Mechanics
Caio Lima Firme
Cover Quantum Mechanics
Caio Lima Firme
Cover C1 Chemistry
Saeed Sahebdelfar
Cover C1 Chemistry
Maryam Takht Ravanchi
Cover Biodiesel Production
Suttichai Assabumrungrat
Cover Biodiesel Production
Suttichai Assabumrungrat



Medizinische Chemie, Pharmaceutical & Medicinal Chemistry, Computational Chemistry & Molecular Modeling, Wirkstoffforschung u. -entwicklung, Drug Discovery & Development, Pharmazeutische u. Medizinische Chemie, Computational Chemistry u. Molecular Modeling, Computational chemistry, Chemistry, Chemie, Arzneimittelentwicklung