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Molecular Pathology in Drug Discovery and Development

J. Suso Platero (Hrsg.)

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John Wiley & Sons img Link Publisher

Naturwissenschaften, Medizin, Informatik, Technik / Chemie

Beschreibung

Covers powerful new tools for drug development Molecular pathology offers tools and techniques that can greatlyenhance the drug discovery and development process, helping to makethe promises of personalized medicine a reality. MolecularPathology in Drug Discovery and Development provides an unmatchedguide to this cutting-edge discipline and its applications topharmaceutical science. With contributions from leading lights in drug discovery, drugdevelopment, and molecular pathology balanced by a consistenteditorial approach, this reference offers both an overview ofmolecular pathology and a close look at the methods as they areapplied to the process of drug discovery and development. Presentedas steps in the drug development process, the coverage includes theuse of molecular pathology to: * Identify and validate new drug candidates * Enhance transcriptional profiling to better find and validatebiomarkers * Assess toxicology * Employ toxicogenomics to identify genes relevant to the safetyof compounds * Identify correct doses for different drugs * Identify patients for treatment * Develop molecular therapies * Further the new techniques of Immunohistochemistry andImmunofluorescence With many tests and treatments already working today, drugresearch and development using molecular pathology has shown itselfan extremely fruitful area. Molecular Pathology in Drug Discoveryand Development gives practitioners an up-to-date resource on thishighly active discipline and its role in furthering pharmaceuticalresearch.

Rezensionen

(The Yale Journal of Biology and Medicine, March 2010)
"Molecular Pathology in Drug Discovery and Development is a well-written book that provides both an overview of how biomarkers may be developed and detailed explanations of how to measure and analyze said biomarkers."
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Schlagwörter

Zell- u. Molekularbiologie, Arzneimittelforschung, Chemistry, Life Sciences, Pharmakologie u. Pharmazeutische Medizin, Wirkstoffforschung u. -entwicklung, Medizin, Medical Science, Drug Discovery & Development, Biowissenschaften, Molekularpathologie, Cell & Molecular Biology, Chemie, Pharmacology & Pharmaceutical Medicine