Leseprobe
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Making Mice
Karen Rader
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Naturwissenschaften, Medizin, Informatik, Technik / Naturwissenschaften allgemein
Beschreibung
Making Mice blends scientific biography, institutional history, and cultural history to show how genetically standardized mice came to play a central role in contemporary American biomedical research.
Karen Rader introduces us to mouse "fanciers" who bred mice for different characteristics, to scientific entrepreneurs like geneticist C. C. Little, and to the emerging structures of modern biomedical research centered around the National Institutes of Health. Throughout Making Mice, Rader explains how the story of mouse research illuminates our understanding of key issues in the history of science such as the role of model organisms in furthering scientific thought. Ultimately, genetically standardized mice became icons of standardization in biomedicine by successfully negotiating the tension between the natural and the man-made in experimental practice.
This book will become a landmark work for its understanding of the cultural and institutional origins of modern biomedical research. It will appeal not only to historians of science but also to biologists and medical researchers.
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Molecular biology, Cancer research, Big Science, Leslie Brent, Max Theiler, Robert Yerkes, Mammary tumor, Pathology, Warren Weaver, Jackson Laboratory, Works Progress Administration, Nicholas Wade, Drosophila, DEPT (medicine), Institution, Physician, The Tumor, Jacques Monod, Mendelian inheritance, E. R. Squibb, Abraham Flexner, Gunther Stent, Birth control, Herbert Spencer Jennings, Inbred strain, Pasteur Institute, Organ procurement, Charles Darwin, Organism, Smithsonian Institution, Harvard University, Medical research, Hermann Joseph Muller, Heredity, Phage group, Model organism, Thomas Hunt Morgan, Laboratory mouse, Breast cancer, Geneticist, Philosophy of biology, Arthur Compton, Funding, Charlotte Auerbach, Bulletin of the Atomic Scientists, Johannes Fibiger, Biologist, Cancer Research Institute, Jean Dausset, George Beadle, Louis Fieser, Mutation, General Education Board, Eugenics, Fancy mouse, William Bateson, C. C. Little, Theodosius Dobzhansky, Fellow of the Royal Society, Atomic Bomb Casualty Commission, Virology, Mutation rate, Animal testing, Baruj Benacerraf, Vivisection, Mutation frequency, Research program, Inbreeding, J. B. S. Haldane, Biology