Leseprobe
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Essentials of Chemical Biology
Andrew D. Miller, Julian A. Tanner
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Naturwissenschaften, Medizin, Informatik, Technik / Mikrobiologie
Beschreibung
"This excellent work fills the need for an upper-level graduate course resource that examines the latest biochemical, biophysical, and molecular biological methods for analyzing the structures and physical properties of biomolecules... This reviewer showed [the book] to several of his senior graduate students, and they unanimously gave the book rave reviews. Summing Up: Highly recommended..." CHOICE Chemical biology is a rapidly developing branch of chemistry, which sets out to understand the way biology works at the molecular level. Fundamental to chemical biology is a detailed understanding of the syntheses, structures and behaviours of biological macromolecules and macromolecular lipid assemblies that together represent the primary constituents of all cells and all organisms. The subject area of chemical biology bridges many different disciplines and is fast becoming an integral part of academic and commercial research. This textbook is designed specifically as a key teaching resource for chemical biology that is intended to build on foundations lain down by introductory physical and organic chemistry courses. This book is an invaluable text for advanced undergraduates taking biological, bioorganic, organic and structural chemistry courses. It is also of interest to biochemists and molecular biologists, as well as professionals within the medical and pharmaceutical industry. Key Features: * A comprehensive introduction to this dynamic area of chemistry, which will equip chemists for the task of understanding and studying the underlying principles behind the functioning of biological macro molecules, macromolecular lipid assemblies and cells. * Covers many basic concepts and ideas associated with the study of the interface between chemistry and biology. * Includes pedagogical features such as: key examples, glossary of equations, further reading and links to websites. * Clearly written and richly illustrated in full colour.
Rezensionen
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"The succinct and lucid presentation style of Essentials Of Chemical Biology will likely make it a popular resource for undergraduate and graduate students interested in the structure and interaction of biologically relevant macromolecules."
"This excellent work fills the need for an upper-level graduate course resource that examines the latest biochemical, biophysical, and molecular biological methods for analyzing the structures and physical properties of biomolecules. Miller (Imperial College London, UK) and Tanner (Univ. of Hong Kong) cover traditional subjects such as binding interactions and catalysis. They also describe biophysical theories and current methods for protein structure determinations such as circular dichroism, X-ray crystallography, neutron diffraction, NMR, EPR, fluorescence, mass spectrometry, and electron and atomic force microscopy. For example, the chapter on solution NMR provides simplified yet high-quality explanations of the key principles of NMR. The well-developed introduction helps students to better follow the more complex information concerning the principles of multidimensional NMR. In addition, the latter part of the chapter offers current applications using a variety of multidimensional NMR spectroscopy experiments in the analysis of proteins, nucleic acid, carbohydrate, and lipid structures. This reviewer showed Essentials of Chemical Biology to several of his senior graduate students, and they unanimously gave the book rave reviews. The work could be improved by better referencing the resource materials within the text and by providing student exercises at the end of each chapter."
"This book seems to fit our needs very well, I would certainly recommend it. I would consider changing the course to reflect material in this book"
-Dr RJ Cox, University of Bristol
"Worth pursuing as an excellent text for structural aspects. Would be very good for postgraduate courses as well"
-Dr N. Botting, University of St Andrews
"Very much worth pursuing. The structure and dynamics approach is most welcome. The proposed text seems to address the omissions of several current texts. This could be the winner for our needs. A recent massive investment in bioinformatics and chemoinformatics means that modelling of structure (& recognition) and manipulation and visualisation of complex molecules is a real teaching possibility for evolving courses"
-Karl Hemming, University of Hertfordshire
"Certainly there is a need for this type of text - its coverage is very comprehensive. A book like this would certainly allow development of existing courses or creation of new ones."
-Dr GA Nickolas, Manchester Met University
"Will be a good new addition to current texts."
-Dr J. Gardiner, UMIST
"I find the overall philosophy and content of the proposed work both exciting and admirable. As far as I am aware, there is no book on the market with a similar coverage. I wish the authors well and think that this is a timely and worthwhile enterprise."
-Dr. Brian Ridge, University of Exeter
Kundenbewertungen
Cell & Molecular Biology, Chemische Biologie, Biochemie u. Chemische Biologie, Chemistry, Biochemie, Life Sciences, Biowissenschaften, Chemie, Biochemistry (Chemical Biology), Organische Chemie, Zell- u. Molekularbiologie, Organic Chemistry