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Mathematical Modelling of Haemodialysis

Cardiovascular Response, Body Fluid Shifts, and Solute Kinetics

Leszek Pstras, Jacek Waniewski

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Springer International Publishing img Link Publisher

Naturwissenschaften, Medizin, Informatik, Technik / Allgemeines

Beschreibung

Beginning with an introduction to kidney function, renal replacement therapies, and an overview of clinical problems associated with haemodialysis, this book explores the principles of the short-term baroreflex regulation of the cardiovascular system and the mechanisms of water and solute transport across the human body from a mathematical model perspective. It synthesizes theoretical physiological concepts and practical aspects of mathematical modelling needed for simulation and quantitative analysis of the haemodynamic response to dialysis therapy.

Including an up-to-date review of the literature concerning the modelled physiological mechanisms and processes, the book serves both as an overview of transport and regulatory mechanisms related to the cardiovascular system and body fluids and as a useful reference for the study and development of mathematical models of dynamic physiological processes.

Mathematical Modelling of Haemodialysis: Cardiovascular Response, Body Fluid Shifts, and Solute Kinetics is intended for researchers and graduate students in biomedical engineering, physiology, or medicine interested in mathematical modelling of cardiovascular dynamics and fluid and solute transport across the human body, both under physiological conditions and during haemodialysis therapy.

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Schlagwörter

ESRD, transport mechanisms, baroreflex regulation, renal replacement therapy, model-based simulations, water and solute transport, end-stage renal disease, short-term cardiovascular baroreflex regulation, haemodialysis, intradialytic hypertension, intradialytic hypotension, regulatory mechanisms, mathematical models, kidney dialysis