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Genetic Damage in Human Spermatozoa

Monica Muratori (Hrsg.), Elisabetta Baldi (Hrsg.)

PDF
ca. 149,79
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Springer International Publishing img Link Publisher

Naturwissenschaften, Medizin, Informatik, Technik / Genetik, Gentechnik

Beschreibung

There are several types of damage that can be found in the male gamete. This book covers the genetic damage in spermatozoa that can originate during spermatogenesis, or during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.

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Schlagwörter

Oxidative damage, chromatin structure, alterations, Epigenetic, gene expression, reproduction, DNA fragmentation