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Mechanisms of Atrial Arrhythmias

Insights from the Development of a Biophysically Detailed Model of the Human Atria

Michael A. Colman

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Springer International Publishing img Link Publisher

Naturwissenschaften, Medizin, Informatik, Technik / Biochemie, Biophysik

Beschreibung

This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac electrophysiology, physics of excitable media, applied mathematics and high performance scientific computing and visualisation. The author uses computer models to provide insights into the underlying mechanisms of the genesis of atrial fibrillation and develops novel techniques for the monitoring of atrial tachycardia.

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Schlagwörter

Electrophysiological Mdelling, Atrial Tchycardia, Pacemaking Mehanisms, Electrical Rmodelling, Cardiac Mdelling, Atrial Fbrillation, Autonomic Crdiac Rgulation, 3D Anatomical Modelling of the Atria