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An Information Technology Framework for Predictive, Preventive and Personalised Medicine

A Use-Case with Hepatocellular Carcinoma

Leonard Berliner (Hrsg.), Heinz U. Lemke (Hrsg.)

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Springer International Publishing img Link Publisher

Naturwissenschaften, Medizin, Informatik, Technik / Allgemeines

Beschreibung

This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC. An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes.

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Schlagwörter

Model Guided Therapy, Predictive, Preventive and Personalised Medicine, Information Technology, Hepatocellular Cancer, Decision Support System, hepatology