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Peptides and Peptide-based Biomaterials and their Biomedical Applications

Peter L. Bergquist (Hrsg.), Anwar Sunna (Hrsg.), Andrew Care (Hrsg.)

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Springer International Publishing img Link Publisher

Naturwissenschaften, Medizin, Informatik, Technik / Nichtklinische Fächer

Beschreibung

Solid-binding peptides have been used increasingly as molecular building blocks in nanobiotechnology as they can direct the assembly and functionalisation of a diverse range of materials and have the ability to regulate the synthesis of nanoparticles and complex nanostructures. Nanostructured materials such as β-sheet fibril-forming peptides and α-helical coiled coil systems have displayed many useful properties including stimulus-responsiveness, modularity and multi-functionality, providing potential technological applications in tissue engineering, antimicrobials, drug delivery and nanoscale electronics. The current situation with respect to self-assembling peptides and bioactive matrices for regenerative medicine are reviewed, as well as peptide-target modeling and an examination of future prospects for peptides in these areas.


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Schlagwörter

Biomedicine, Biomaterials, Biopolymers, Nanomaterials, Protein-Ligand Interactions, Peptides