Molecular Diagnostics in Cytopathology
John M. Stewart (Hrsg.), Gilda da Cunha Santos (Hrsg.), Paul A. VanderLaan (Hrsg.), Sinchita Roy-Chowdhuri (Hrsg.)
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Springer International Publishing
Naturwissenschaften, Medizin, Informatik, Technik / Klinische Fächer
Beschreibung
Molecular diagnostics are increasingly used to help guide targeted therapy in solid organ tumors and hematologic malignancies. A large proportion of molecular testing is performed on limited-volume samples obtained via minimally invasive techniques, such as fine needle aspiration. Increasingly, cytopathologists play an essential role in this process, both in the triage of specimens during rapid on-site evaluation and in the evaluation of archival samples to determine suitability for ancillary testing. Therefore, it is imperative that practicing cytopathologists stay abreast of up-to-date diagnostic, prognostic, and predictive ancillary tests that can be used on limited cytologic material. This is a challenge since the landscape of known genomic alterations is constantly evolving and the subsequent set of testing options is ever expanding.
Kundenbewertungen
Laboratory processing, FISH assays, RT-PCR assays, Solid organ malignancies, Human papillomavirus, cytology specimen