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Microarray Quality Control

Wei Zhang, Jaakko Astola, Ilya Shmulevich, et al.

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125,99 €
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John Wiley & Sons img Link Publisher

Naturwissenschaften, Medizin, Informatik, Technik / Mikrobiologie

Beschreibung

Microarray technology provides researchers in the life sciences with a revolutionary tool for measuring gene expression. However, this highly developed process involves multiple steps, from sample selection to data analysis, each susceptible to potentially costly errors. Without sound quality control, experimental microarrays may produce useless or, even worse, misleading results. Microarray Quality Control provides a comprehensive resource for ensuring quality control in every step of this complex process. From experimental design to data processing, analysis, and interpretation, the emphasis in this text remains on practical advice for each stage of planning and running a microarray study. Chapters cover: * Quality of biological samples * Quality of DNA * Hybridization protocols Scanning * Data acquisition * Image analysis * Data analysis Written for the broad group of workers-biologists, mathematicians, statisticians, engineers, physicians, and computational scientists-involved in microarray studies, Microarray Quality Control features a straightforward style easily accessed by various disciplines. Useful checklists and tips help ensure the integrity of results, and each chapter contains a thorough review of pertinent literature. The only complete, systematic treatment of the topic available, Microarray Quality Control offers students and practitioners an invaluable resource for improving experimental quality and efficiency.

Rezensionen

(Journal of Statistical Computation and Simulation, September 2005)
"...a thought-provoking book...highly useful to statisticians, biologists, engineers, medical researchers, and medical scientists."
(Annals of Biomedical Engineering, June 2005)
"The book may be recommended for all researchers and students working with the DNA microarray technology"
(Journal of the American Statistical Association, June 2005)
"...a useful source of ideas and potential issues."
(E-STREAMS, March 2005)
"This book is recommended [for] all libraries serving researchers using high-throughput techniques."
(Engineering in Life Sciences, Vol.5, No.5, 2004)
"...an essential laboratory resource for scientists studying gene regulation and for all experimental biologists interested in the emerging practical applications of microarrays."
(Genetic Engineering News, Vol. 24, No. 6, March 15, 2004)
"...offers practical guidance for each stage of planning and execution of microarray studies..."
(Drug Discovery and Development, March 2004)
"...the breadth of issues encompassed by quality control in microarray studies are covered...a valuable systematic treatment of microarray quality control."
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Schlagwörter

Biowissenschaften, Biotechnology, Chemie, Bioinformatik u. Computersimulationen in der Biowissenschaften, Zell- u. Molekularbiologie, Molekularbiologie, Biotechnologie i. d. Chemie, Life Sciences, Cell & Molecular Biology, Bioinformatics & Computational Biology, Chemistry