The Alzheimer Conundrum

Entanglements of Dementia and Aging

Margaret Lock

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Princeton University Press img Link Publisher

Geisteswissenschaften, Kunst, Musik / Pädagogik

Beschreibung

Why our approaches to Alzheimer's and dementia are problematic and contradictory

Due to rapidly aging populations, the number of people worldwide experiencing dementia is increasing, and the projections are grim. Despite billions of dollars invested in medical research, no effective treatment has been discovered for Alzheimer's disease, the most common form of dementia. The Alzheimer Conundrum exposes the predicaments embedded in current efforts to slow down or halt Alzheimer’s disease through early detection of pre-symptomatic biological changes in healthy individuals.

Based on a meticulous account of the history of Alzheimer’s disease and extensive in-depth interviews, Margaret Lock highlights the limitations and the dissent associated with biomarker detection. Lock argues that basic research must continue, but should be complemented by a public health approach to prevention that is economically feasible, more humane, and much more effective globally than one exclusively focused on an increasingly harried search for a cure.

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Schlagwörter

Physician, Syndrome, Neurology, Processing (Chinese materia medica), Cell death, Family support, Genome-wide association study, Geneticist, Family history (medicine), Medical diagnosis, Clinical trial, Amyloid beta, Genetic counseling, Caregiver, Positron emission tomography, Clinician, Prevalence, Pharmaceutical industry, Cardiovascular disease, General practitioner, Diagnosis, Early-onset Alzheimer's disease, Oxidative stress, Risk factor, Dementia, Mental disorder, Allele, Psychiatry, Scientist, Amyloid, Neurofibrillary tangle, Genetic testing, Neurodegeneration, Neuropathology, Finding, Vascular dementia, Genotyping, Inflammation, Uncertainty, Alzheimer's Association, Public health, Pharmaceutical drug, Mild cognitive impairment, Neuroimaging, Research assistant, Psychiatrist, Symptom, Toxin, Biomarker, Genotype, Principal investigator, Follow-up, Technology, Apolipoprotein E, Amnesia, Funding, Model organism, National Institute on Aging, Epidemic, Drug development, Cerebrospinal fluid, Human subject research, Molecular biology, Old age, Pathology, Alzheimer's disease, Age of onset, Epidemiology, Specialty (medicine), Disease