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Therapeutic Rhodium Complexes

Mushtaq Ahmad Lone, Afzal Hussain, Waseem A. Wani, et al.

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Springer Nature Switzerland img Link Publisher

Naturwissenschaften, Medizin, Informatik, Technik / Anorganische Chemie

Beschreibung

This book describes the emergence and recent advances in the design and development of rhodium complexes as therapeutic agents. Different classes of anticancer rhodium complexes with particular emphasis on ligands containing nitrogen-oxygen donor atoms are presented. Anticancer rhodium complexes of N-heterocyclic carbenes are described, while half-sandwich, heterobimetallic, and multinuclear rhodium complexes are discussed. Therapeutic applications of rhodium complexes beyond cancer such as antibacterial agents or antiviral agents are also analyzed, among others. Their mechanism of action is overviewed in detail, and the authors thoroughly comment on the challenges and future outlooks of research in the development of rhodium metallodrugs. This title highlights the important research carried out in the development of therapeutic rhodium complexes and is of great interest to graduates and researchers working in the area of rhodium-based therapeutic drugs.

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Schlagwörter

DNA interacting agents, Half sandwich rhodium complexes, Bioinorganic chemistry, Antibacterial agents, Anticancer rhodium complexes, N-heterocyclic carbene ligands