Surface Plasmon Resonance Imaging

Basic Theory and Practical Methodology

Yi Chen

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Springer Nature Singapore img Link Publisher

Naturwissenschaften, Medizin, Informatik, Technik / Theoretische Chemie

Beschreibung

This book introduces the fundamentals, instruments, methodology, and applications of surface plasmon resonance imaging (SPRi) and related techniques. It provides an overview of SPRi development and an easy-to-understand interpretation of theory and operation principles. Some unique ideas proposed by the authors to design and set up SPRi devices and methods are disclosed for the first time. Crucial manipulation experiences are also summarized here, including chip surface functionalization, sensitivity enhancement and coupling of SPRi with other analytical techniques. The application of SPRi for molecular interaction study, featuring high throughput, label-freeness, and physiologically compatible analysis, is discussed in detail. This book is of interest and useful to a wide readership in bioanalytical chemistry, molecular biology, and many related interdisciplinary fields.


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Schlagwörter

SPRI, Plasmonic Nanobiosensors, Surface Functionalization, Thermodynamic and Kinetic Analysis, Surface Plasmon Resonance Microscopy, Biomolecular Interaction Analysis, Pharmaceutical Screening