Targeting Epigenetics in Inflammatory Lung Diseases

Brian G. Oliver (Hrsg.), Gaurav Gupta (Hrsg.), Piyush Dave (Hrsg.), Md Khadem Ali (Hrsg.), Kamal Dua (Hrsg.)

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Springer Nature Singapore img Link Publisher

Naturwissenschaften, Medizin, Informatik, Technik / Pharmazie

Beschreibung

This book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer, pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections. It also explores post-translational modifications in DNA and histones for improving the understanding of lung diseases. This book helps in understanding the epigenetic mechanisms towards the development of novel diagnostic and therapeutic approaches. Further, the book provides insight into the underlying molecular mechanisms involved in the epigenetic regulation of inflammation, which may have novel implications in designing small molecule inhibitors that target the epigenetic machinery for the effective treatment of a variety of inflammation‑related diseases. This book is a valuable resource for academics, research and industry professionals working in respiratory biology.

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Schlagwörter

Inflammation, Lung diseases, Histone acetylation, DNA methylation, Epigenetics